Table 2.

Steady-state activation and inactivation properties of Ca_v3.2 variants

	m∞		h∞
	V₅₀ (mV)	k	V₅₀ (mV)	k
Wild-type	−54.8 ± 0.4	7.4 ± 0.1 (43)	−85.5 ± 0.8	−7.2 ± 0.2 (29)
F161L	−53.3 ± 1.0	7.2 ± 0.2 (11)	−82.3 ± 0.9^*	−5.9 ± 0.1 (7)^**
E282K	−53.4 ± 0.7	7.9 ± 0.2 (15)^**	−83.9 ± 1.2	−6.3 ± 0.1 (7)^*
C456S	−59.9 ± 0.9^**	7.4 ± 0.1 (26)	−85.1 ± 1.0	−6.8 ± 0.1 (16)
G499S	−54.2 ± 0.6	7.4 ± 0.2 (13)	−85.5 ± 1.6	−7.2 ± 0.4 (8)
P648L	−53.9 ± 0.5	7.5 ± 0.2 (19)	−81.7 ± 1.7^*	−6.7 ± 0.3 (8)
R744Q	−53.9 ± 0.6	7.4 ± 0.1 (15)	−84.2 ± 2.0	−6.6 ± 0.3 (7)
A748V	−56.2 ± 1.1	7.1 ± 0.2 (9)	−85.5 ± 1.4	−6.6 ± 0.2 (5)
G773D	−51.8 ± 1.0^**	8.0 ± 0.2 (15)^**	−82.2 ± 1.1^*	−8.0 ± 0.4 (8)^*
G784S	−54.0 ± 0.6	7.3 ± 0.2 (21)	−85.4 ± 1.6	−6.6 ± 0.3 (10)
R788C	−52.5 ± 0.9^*	7.9 ± 0.2 (13)^*	−83.2 ± 1.1	−8.5 ± 0.2 (7)^**
G773D-R788C	−53.0 ± 0.9	7.4 ± 0.1 (7)	−84.8 ± 1.5	−8.5 ± 0.5 (7)^**
V831M	−52.2 ± 0.8^**	7.5 ± 0.1 (14)	−86.5 ± 1.3	−6.7 ± 0.2 (8)
G848S	−54.6 ± 0.8	7.1 ± 0.1 (16)	−83.3 ± 2.1	−6.6 ± 0.3 (7)
D1463N	−52.8 ± 0.8	7.4 ± 0.2 (8)	−85.8 ± 0.7	−6.3 ± 0.4 (4)

The values of V₅₀ and k were calculated for each cell and then averaged. Data shown are mean ± SEM from the number of cells shown in parentheses. Statistically significant differences (determined with Student's t test) are marked with a single asterisk if p < 0.05 and with a double asterisk if p < 0.01.