Reinforcing effects of anandamide in individual monkeys
| Vehicle | Anandamide, 40 μg/kg per injection | ||||
|---|---|---|---|---|---|
| Monkey | Self-administration history | Injections per session | Responses per second | Injections per session | Responses per second |
| 70F4 | None | 3.00 ± 1.15 | 0.01 ± 0.01 | 46.67 ± 0.88 | 0.62 ± 0.04 |
| 66B2a | None | 4.67 ± 1.76 | 0.02 ± 0.01 | 47.00 ± 1.00 | 0.64 ± 0.06 |
| 6754 | THC | 8.33 ± 3.33 | 0.03 ± 0.01 | 50.00 ± 5.00 | 1.18 ± 0.44 |
| 1568 | THC | 11.00 ± 5.86 | 0.05 ± 0.03 | 51.00 ± 0.58 | 1.04 ± 0.08 |
| 67F4 | THC | 4.00 ± 1.00 | 0.02 ± 0.00 | 42.00 ± 1.00 | 0.40 ± 0.03 |
| 1574 | Methohexital | 5.33 ± 1.45 | 0.02 ± 0.01 | 45.33 ± 4.70 | 0.66 ± 0.21 |
| Mean ± SEM | 6.06 ± 1.23 | 0.02 ± 0.01 | 47.00 ± 1.33 | 0.76 ± 0.12 | |
The values are calculated as mean ± SEM of the last three of five sessions under each condition.
↵ a Monkey initially learned to self-administer anandamide but, after acquisition and subsequent extinction, was used only for methanandamide experiments.