Table 2.

ELISA Aβ levels (means ± SE)

Assay PDAPP plus saline PDAPP plus 10D5 p
Plasma Aβ40a 60.5 ± 7 143.2 ± 17.6 0.0001
Plasma Aβ42a 21.9 ± 5.5 544 ± 253.9 0.04
Carbonate-soluble hippocampal Aβ40b 10.27 ± 7.22 8.88 ± 1.71 NS
Carbonate-insoluble hippocampal Aβ40b 276.59 ± 122.23 190.13 ± 41.15 NS
Carbonate-soluble hippocampal Aβ42b 37.82 ± 8.35 34.98 ± 5.38 NS
Carbonate-insoluble hippocampal Aβ42b 1,275.15 ± 743.33 939.25 ± 232.44 NS
  • a Picograms of protein per milliliter.

  • b Picograms of protein per microliter.