Table 1.

Physiological variables

Before MCAO During MCAO After MCAO
Vehicle SB-3CT Vehicle SB-3CT Vehicle SB-3CT
MABP (mmHg) 76.17 ± 4.65 78.68 ± 3.17 76.22 ± 4.90 79.49 ± 3.48 76.91 ± 4.43 76.12 ± 2.89
pH 7.274 ± 0.020 7.313 ± 0.060 7.177 ± 0.078 7.106 ± 0.025 7.139 ± 0.078 7.170 ± 0.027
PCO2 (mmHg) 37.27 ± 1.28 40.70 ± 7.828 50.50 ± 11.33 44.95 ± 14.55 51.93 ± 10.58 43.90 ± 5.28
PO2 (mmHg) 252.8 ± 6.7 230.8 ± 31.7 259.2 ± 21.9 214.5 ± 10.3 242.5 ± 6.0 245.4 ± 24.0
Na+ (mmol/L) 154.9 ± 1.1 155.7 ± 1.8 158.4 ± 2.4 157.20 ± 0.5 158.7 ± 2.6 157.7 ± 2.0
Ca2+ (mmol/L) 1.113 ± 0.003 1.150 ± 0.021 1.133 ± 0.014 1.117 ± 0.081 1.157 ± 0.023 1.100 ± 0.074
Glucose (mg/dl) 147.7 ± 7.5 160.7 ± 13.2 148.0 ± 11.5 162.70 ± 13.3 147.7 ± 11.7 154.3 ± 12.6
  • Note that we observed no significant changes in the physiological values of blood gases and electrolytes in animals with or without MCAO. Blood was drawn 5 min before ischemia, 15 min after ischemia, and 15 min after reperfusion. Data are mean ± SEM (n = 5). MABP Mean arterial blood pressure.