Spontaneous difference (fold increase) | Orexin | Tyrosine hydroxylase | NOS-1 | NOS-2 | VIP | PRL | Interferon type I receptor |
---|---|---|---|---|---|---|---|
(−/−) | 0.92 ± 0.042a | 0.77 ± 0.54 | 0.98 ± 0.297 | 0.85 ± 0.106 | 0.89 ± 0.106 | 4.45 ± 1.797 | 0.92 ± 0.042 |
(+/−) | 1.01 ± 0.050 | 1.05 ± 0.109 | 1.03 ± 0.071 | 1.08 ± 0.145 | 1.04 ± 0.086 | 2.67 ± 1.288a | 1.01 ± 0.050 |
p | 0.141 | 0.028* | 0.622 | 0.153 | 0.262 | 0.411 | 0.141 |
Fold increase after PRL replacement | Orexin | Tyrosine hydroxylase | NOS-1 | NOS-2 | VIP | PRL | Interferon type I receptor |
---|---|---|---|---|---|---|---|
(−/−) | 0.97 ± 0.094 | 1.29 ± 0.170 | 1.03 ± 0.051 | 1.04 ± 0.069 | 0.63 ± 0.103 | 5.22 ± 2.047 | 1.17 ± 0.63 |
(+/−) | 1.05 ± 0.106 | 1.12 ± 0.176 | 1.05 ± 0.093 | 1.03 ± 0.083 | 1.05 ± 0.109 | 1.30 ± 0.486 | 1.05 ± 0.100 |
p | 0.573 | 0.481 | 0.860 | 0.936 | 0.008* | 0.096 | 0.289 |
aValues are ΔΔCt values (see Materials and Methods) ± SEM. Variance in the PRL values was high, therefore values for (+/−) mice are not close to 1.0.
*p < 0.05.