Table 1.

Subjective scoring results of status of white matter tracts in developing Bcl-x knock-out mice

Axonal tracts P0 P3 P5 P7 Adult
Interhemispheric
Corpus callosum + + + +
Anterior commissure + + +
Posterior commissure
Subcortical projections
Internal capsule
Cerebral peduncle
Pyramidal tract
Medial lemniscus
Projections to/from thalamus
Mammillo-thalamic tract
Fasciculus retroflexus
Medial forebrain bundle
Limbic
Fimbria + + + +
Hippocampal commissure +
Fornix
Stria terminalis
Cingulum
Cerebellar
Superior cerebellar peduncle
Middle cerebellar peduncle
Inferior cerebellar peduncle
  • −, No apparent abnormalities; +, significant reduction in size.