Percentages of whole chromosome 21 gain and loss in neurons and non-neuronal cells isolated from the brains of three different individuals and sorted by FACS
| Aneuploid karyotype | |||||||
|---|---|---|---|---|---|---|---|
| Age (years) | Cell type | % Disomy | % Tetrasomy | % Monosomy | % Trisomy | % Aneuploidy | Mean chromosome number |
| 2 | Neurons | 95.4 | 1.2 | 2.0 | 1.4 | 3.4 | 2.02 |
| 2 | Non-neuronal cells | 95.8 | 0.9 | 2.5 | 0.8 | 3.3 | 2.00 |
| 35 | Neurons | 96.4 | 0.8 | 1.8 | 1.0 | 2.8 | 2.01 |
| 35 | Non-neuronal cells | 95.0 | 1.6 | 2.5 | 0.9 | 3.4 | 2.02 |
| 48 | Neurons | 96.5 | 1.3 | 1.5 | 0.8 | 2.3 | 2.02 |
| 48 | Non-neuronal cells | 94.7 | 1.4 | 3.1 | 0.8 | 3.9 | 2.01 |
| Average | Neurons | 96.1 | 1.1 | 1.8 | 1.1 | 2.8 | 2.0 |
| Average | Non-neuronal cells | 95.2 | 1.3 | 2.7 | 0.8 | 3.5 | 2.0 |