Differential effect of emotional distracters in dorsal executive versus ventral affective neural systems
| Neural system | Brodman Area | Side | Talairach coordinates | t values of paired contrasts | Time (s) | ||||
|---|---|---|---|---|---|---|---|---|---|
| x | y | z | Scram > Emo | Scram > Neu | Neu > Emo | ||||
| Dorsal executive | |||||||||
| dlPFC | 9/46 | R | 46 | 38 | 22 | 9.6 | 6.5 | 4.3 | 12 |
| 9 | L | −34 | 29 | 26 | 5.1 | 5.4 | 12 | ||
| LPC | 40 | R | 46 | −54 | 40 | 9.7 | 5.6 | 5.4 | 12 |
| 40 | L | −53 | −54 | 43 | 5.3 | 5.1 | 12 | ||
| pCG | 31 | M | 4 | −29 | 35 | 5.6 | 4.1 | 12 | |
| BG | cn | R | 18 | 24 | 4 | 5.8 | 4.2 | 3.1a | 12 |
| x | y | z | Emo > Scram | Emo > Neu | Neu > Scram | ||||
| Ventral affective | |||||||||
| vlPFC | 45 | R | 53 | 28 | 12 | 9.1 | 9.4 | 4.0 | 14 |
| 45/47 | L | −50 | 27 | 4 | 5.4 | 4.6 | 16 | ||
| sgCG | 25 | M | 2 | 13 | −16 | 6.2 | 4.2 | 14 | |
| Insula | 13 | R | 40 | −12 | −1 | 5.1 | 3.8 | 14 | |
| Amygdala | R | 22 | −1 | −12 | 10.0 | 6.0 | 3.8 | 16 | |
| L | −22 | −4 | −12 | 7.7 | 7.5 | 3.0a | 16 | ||
| HC | R | 28 | −14 | −11 | 5.6 | 4.6 | 4.9 | 16 | |
| L | −24 | −12 | −8 | 7.6 | 4.6 | 5.3 | 16 | ||
| Hthal | M | 0 | 0 | −7 | 10.0 | 5.0 | 14 | ||
| Midbrain | M | 2 | −15 | 3 | 6.9 | 7.4 | 12 |
t values of paired contrasts between the conditions of interest as a result of whole-brain voxel-based analyses (p < 0.001; t > 3.79) are shown for typical dorsal executive and ventral affective brain regions. The x, y, z coordinates denote the location of the peak voxel in Talairach space (Talairach and Tournoux, 1988). The effects identified during the delay interval typically peaked between 12 and 16 s after the onset of the memoranda (TRs, 6–8 after onset). Emo, Emotional; Neu, neutral; Scram, scrambled; R, right; L, left; M, middle; pCG, posterior cingulated gyrus; BG, basal ganglia; cn, caudate nucleus; sgCG, subgenual cingulate gyrus; HC, hippocampus; Hthal, hypothalamus.
↵a Significant at p < 0.005 (t > 2.97).