Table 3.

Blockade of DAergic effects on input resistance by blockers of h-channels

DrugBaseline (with drug)After DA
K+-channel blockers
    TEA (1 mm; n = 6)157.1 ± 6.2141.9 ± 5.8*
    4-AP (3 mm; n = 8)121.5 ± 5.3109.7 ± 5.7*
    Ba2+ (250 μm; n = 7)144.1 ± 4.9131.4 ± 4.2*
    Cs+ (10 mm; n = 9)176.8 ± 4.4178.1 ± 5.1
Ca2+-channel blockers
    Cd2+ (200 μm; n = 5)110.6 ± 6.192.7 ± 5.4*
    Nimodipine/Ni2+ (10/50 μm; n = 5)108.0 ± 5.095.0 ± 4.8*
Ca2+ chelator
    BAPTA (20 μm; n = 5)117.2 ± 6.3107.9 ± 6.1*
Ca2+-activated K+-channel blocker
    UCL1684 (100 nm; n = 6)103.3 ± 4.892.5 ± 4.9*
h-channel blocker
    ZD7288 (20 μm; n = 11)144.2 ± 4.2149.7 ± 4.2
  • * p < 0.05, paired t test.

  • Not significant.