Table 1.

Properties of the cholinergic mEPSCs in different Kenyon cell populations

Kenyon cell population n Frequency (Hz) Amplitude (pA) Rise time (ms) Decay τ (ms) IR (GΩ) AR (MΩ)
OK107, GFP+ 14 0.24 ± 0.07 4.0 ± 0.3 1.53 ± 0.09 5.23 ± 0.41 1.00 ± 0.05 14.7 ± 0.4
Wild type 6 0.19 ± 0.07 4.3 ± 0.5 1.51 ± 0.11 6.73 ± 1.43 0.99 ± 0.09 14.1 ± 0.6
201Y, GFP± 5 0.26 ± 0.07 3.8 ± 0.2 1.23 ± 0.15 4.85 ± 0.38 1.06 ± 0.16 14.8 ± 1.3
201Y GFP- 6 0.22 ± 0.07 4.9 ± 0.6 1.21 ± 0.14 4.45 ± 1.31 1.13 ± 0.11 13.6 ± 1.0
  • Data were determined from cells in which stable whole-cell recordings were maintained for at least 3 min. The amplitude, rise time, and decay data (mean ± SEM) were determined from the ensemble average mEPSCs, constructed from 18-255 individual events in each neuron recorded at a holding potential of -75 mV. Decay time constant was determined from a single exponential fit (90-10%). The criteria for inclusion of individual mEPSCs were a rise time <2.5 ms and an amplitude of >3 pA. The input resistance (IR) and access resistance (AR) for each cell were determined on-line using the membrane test function (Clampex 9.0; Molecular Devices). No significant differences were detected in these properties between the different Kenyon cell populations examined (ANOVA, p > 0.05).