Comparison of mIPSC properties in wild-type and heterozygote mutant mice
| Genotype | Mean age (d) | Rise time (ms) | Amplitude (pA) | Decay time (ms) | mIPSC frequency (Hz) | n |
|---|---|---|---|---|---|---|
| Wild type | 32 ± 3 | 0.9 ± 0.1 | 71.7 ± 3.5 | 4.9 ± 0.2 | 1.6 ± 0.3 | 23 |
| spa/+ | 36 ± 9 | 1.0 ± 0.1 | 65.0 ± 4.5 | 4.7 ± 0.2 | 1.1 ± 0.2 | 20 |
| spd/+ | 73 ± 16 | 1.0 ± 0.1 | 56.6 ± 2.7a | 4.7 ± 0.2 | 1.6 ± 0.2 | 23 |
| ot/+ or +/+ | 16–18 | 0.8 ± 0.1 | 49.1 ± 4.1a | 4.8 ± 0.2 | 1.5 ± 0.3 | 14 |
↵aSignificant difference (p < 0.05) to wild-type (+/+) controls (based on multivariate ANOVA with genotype as within factor and Student–Newman–Keuls post hoc tests).