Cosinor analysis of the circadian rhythm of ingestion in Ucn-2 knock-out mice and their wild-type littermates
| Female | Male | |||
|---|---|---|---|---|
| Wild type | Ucn-2 KO | Wild type | Ucn-2 KO | |
| Water intake | ||||
| Amplitude (μl/h) | 383 ± 54 | 234 ± 24* | 254 ± 42 | 201 ± 58 |
| MESOR (μl/h) | 304 ± 54 | 254 ± 23 | 206 ± 26 | 215 ± 40 |
| Peak (μl/h) | 686 ± 101 | 488 ± 28* | 462 ± 65 | 415 ± 93 |
| Nadir (μl/h) | −79 ± 42 | 19 ± 38 | −47 ± 30 | 14 ± 37 |
| Acrophase (h after dark onset) | 3.6 ± 0.5 | 3.9 ± 1.1 | 5.9 ± 0.1 | 4.6 ± 1.4 |
| Cosinor fit (r) | 0.75 ± 0.05 | 0.73 ± 0.07 | 0.83 ± 0.02 | 0.76 ± 0.06 |
| Food intake | ||||
| Amplitude (mg/h) | 116 ± 16 | 102 ± 11 | 124 ± 24 | 102 ± 6 |
| MESOR (mg/h) | 163 ± 12 | 160 ± 12 | 163 ± 12 | 186 ± 19 |
| Peak (mgl/h) | 280 ± 6 | 262 ± 18 | 287 ± 32 | 288 ± 17 |
| Nadir (mg/h) | 47 ± 28 | 58 ± 15 | 40 ± 20 | 83 ± 21 |
| Acrophase (h after dark onset) | 3.7 ± 0.8 | 3.5 ± 0.7 | 4.6 ± 0.6 | 3.5 ± 0.8 |
| Cosinor fit (r) | 0.78 ± 0.07 | 0.85 ± 0.04 | 0.90 ± 0.02 | 0.90 ± 0.02 |
↵*p < 0.05 versus WT.