Table 1.

Offspring of RPTP-σ and RPTP-δ mutant mice derived from parental animals heterozygous for both mutations

Genotype (σ · δ)Predicted ratio (%)Observed ratio (%)
E18P04 Weeks
+/+ · +/+6.256.859.687.53
+/− · +/+12.5010.9619.3525.09
−/− · +/+6.254.115.533.58
+/+ · +/−12.5012.338.2917.20
+/− · +/−25.0032.8821.2035.84
−/− · +/−12.509.5915.672.87
+/+ · −/−6.259.5924.296.45
+/− · −/−12.508.229.221.43
−/− · −/−6.255.483.23a0.00
(n = 73)(n = 217)(n = 279)
  • a Ratio includes animals found dead at birth.