Table 1.

Patient characteristics, hippocampal volume reductions, and neuropsychological test scores

SubjectHandednessHippocampusWAIS-IIIWMS-IIIWorking memory
z-scoreVIQPIQFSIQGMIDRICFTWMIDigit SpanArithSent Rept
0001RN/A8310090546429386N/A
1606R−3.9994899166611176798
1846R−4.23897984576268510711
2144R−3.921029499565739911912
2363R−2.641128398737458881110
2563LN/A919894637479914613
  • Hippocampal z-scores represent the combined (left and right hemisphere) studentized residuals of hippocampal volume relative to a group of 43 comparison subjects (Allen et al, 2006). WAIS-III, Wechsler adult intelligence scale-III; VIQ, verbal IQ; PIQ, performance IQ; FSIQ, full-scale IQ; WMS-III, Wechsler memory scale-III; GMI, general memory index; DRI, delayed recall index. For the WMS-III, the DRI is an average of the auditory delayed index and visual delayed index. These tests yield mean scores in the normal population of 100 with an SD of 15. CFT, Complex figure test [delayed recall raw score (total possible correct = 36)]; WMI, working memory index; WMS-III, Wechsler memory scale-III; DS, digit span subtest; WAIS-III, age-corrected scaled score; Arith, arithmetic subtest; WAIS-III, age-corrected scaled score; Sent Rept, sentence repetition subtest, multilingual aphasia examination, raw score.