Table 1.

PHCCC inhibits DNA synthesis in D283med incubated in the presence of serum or EGF

[3H]thymidine incorporation (cpm/well)
NoneFCS (10%)EGF (10 nm)
Controls5600 ± 97038,000 ± 660026,500 ± 3200
PHCCC (30 μm)2300 ± 260*21,000 ± 3500*19,000 ± 700*
  • Values are means ± SEM of 12 determinations. *p < 0.05 (Student's t test) versus the respective controls.