Table 2.

Percentage of reporter+ cells that express the indicated phenotypic markers (mean ± SEM) 30 d after recombination

RegionGFAPDcxNeuNRip
SVZ62.2 (±4.7)39.1 (±2.9)00
OB26.8 (±2.9) * 59.0 (±5.1)2.8 (±0.7)
Cortex57.9 (±4.1) * 0.3 (±0.02)14.1 (±4.3)
Hippoc. DG9.9 (±1.1)ND89.9 (±2.1)0
Hippoc. CA68.1 (±7.0) * <0.1%0
Hippoc. WM80.1 (±5.5) * <0.1%4.1 (±0.8)
CB ML74.0 (±3.6) * <0.1%0
CB WM68.0 (±7.1) * 012.4 (±5.3)
  • GCE transgenic mice, crossed with the R26R or the Z/EG reporter lines, were injected with OHT at P5 and analyzed at P35 (N, between 3 and 6 animals per group). These phenotypes are not meant to be inclusive of every cell and the percentages do not always add to 100%. Abbreviations are as in Table 1. Reporter+ cells were sampled throughout the region of interest by unbiased sampling methods using the optical fractionator method. ND, Not determined.

  • * Marker not expressed.