Quantitative analysis of amperometric spikes
| 1st stimulationa | 2nd stimulationb | |
|---|---|---|
| Imax (pA) | 15.4 ± 7.4 | 24.8 ± 8.3*** |
| t1/2(ms)c | 37.6 ± 4.2 | 24.3 ± 5.0* |
| Quantal size (pC) | 0.7 ± 0.2 | 1.0 ± 0.2* |
| Rise (pA/ms) | 1.3 ± 0.4 | 2.0 ± 0.3** |
| Foot frequency (%)d | 54.9 ± 13.0 | 58.1 ± 7.6 |
| Foot Imax (pA) | 0.3 ± 0.1 | 0.5 ± 0.2* |
| Foot charge (fC) | 48 ± 22 | 103 ± 35* |
The second stimulation-induced amperometric spikes were compared with the first stimulation-induced spikes. Data are shown as means ± SEM values.
↵*p < 0.05;
↵**p < 0.01;
↵***p < 0.001.
↵aOne-hundred ninety-two and
↵b260 amperometric spikes were averaged and analyzed by using a macro program (Mosharov and Sulzer, 2005).
↵cHalf-width of spikes.
↵dFrequency of spikes having prespike foot among total amperometric spikes.