Table 2.

Current-clamp properties of DRG cells transfected with the WT Nav1.7 or the A863P mutation

NRinput (MΩ)RMP (mV)Threshold (pA)Spike amplitude (mV)Repetitive firing
WT32589 ± 52−56.9 ± 1.4248 ± 32111 ± 213 of 32
A863P31728 ± 68−50.4 ± 1.4*157 ± 25**109 ± 216 of 31
  • *p < 0.01 compared to WT; **p < 0.05 compared to WT.