Table 1.

NET-immunoreactive profiles in the prefrontal cortex of control and chronically stressed rats

ControlStress
Number of subjects1616
Area of tissue examined (μm2)763,902795,275
Number of NET-ir profiles per 1000 μm2 of tissue1.131.07
Mean area of NET-ir profiles (μm2)0.370.33
Mean density of gold labeling for NET (particles per unit area)24.227.7
Percentage of gold labeling for NET on the plasma membrane29%51%*
Percentage of NET-ir profiles dually labeled for TH13%32%**
Percentage of NET-ir profiles forming synapses in single sections18%14%

  • ↵*Poisson regression; χ2 = 9.1; df = 1; p = 0.003.

  • ↵**Logistical regression; χ2 = 61.41; df = 1; p ≤ 0.001.

  • All other comparisons, not significant.