Table 2.

Effects of TARPs on IKA/IGlu ratios of heteromeric AMPA receptors

γ2γ3γ4γ8
GluR1(Q)o + GluR2(R)i5.6 ± 0.35.4 ± 0.59.5 ± 0.6***1.7 ± 0.1***11.1 ± 0.6***
GluR3(Q)o + GluR2(R)i13.1 ± 1.26.7 ± 0.4***9.8 ± 0.9*11.4 ± 0.79.7 ± 0.9*
GluR1(Q)i + GluR4(Q)i2.6 ± 0.811.3 ± 1.7***17.9 ± 1.9***6.0 ± 0.9**15.1 ± 2.6***
  • Calculation was performed as described for Table 1. The nomenclature of the AMPA receptor subunits is explained in Table 1.

  • *p < 0.05;

  • **p < 0.01;

  • ***p < 0.005.