Table 1.

Effects of ACPT-I injection into the globus pallidus on the number of premature responses

PrePostACPT-I (nmol/μl)
012.55
Globus pallidus
    Sham (n = 10)58.0 ± 5.964.4 ± 7.365.2 ± 15.7104.4 ± 22.1206.4 ± 29.3*,**,***272.1 ± 71.4*,**,***
    6-OHDA (n = 15)64.7 ± 15.664.6 ± 13.660.4 ± 10.6122.8 ± 23.2184.4 ± 32.8*,**,***176.5 ± 38.1*,**,***
  • Values correspond to the mean number of premature responses ±SEM on different sessions: four sessions preceding the surgery (Pre) and four postoperative sessions (Post) corresponding to the days before infusion of ACPT-I at various doses (days 22, 26, 30, and 34).

  • *p< 0.05, Fisher's PLSD test, compared with preoperative performance after significant ANOVA.

  • **p< 0.05, Fisher's PLSD test, compared with postoperative performance after significant ANOVA.

  • ***p< 0.05, Fisher's PLSD test, compared with vehicle infusion after significant ANOVA.