Table 3.

Effects of picrotoxin injection into the globus pallidus or the substantia nigra pars reticulata on the number of premature responses

PrePostPicrotoxin
Globus pallidus
    Sham (n = 6)38.2 ± 12.149 ± 12.4221.5 ± 104.8*,**
    6-OHDA (n = 6)45 ± 1233.7 ± 5.1172.3 ± 49.3*,**
Substantia nigra
    Sham (n = 8)38.6 ± 7.236.7 ± 6.531.13 ± 5.6
    6-OHDA (n = 8)38.6 ± 4.945 ± 8.651.63 ± 9.3
  • The values correspond to the mean number of premature responses ±SEM recorded on different sessions of the preoperative (Pre) or postoperative (Post) period. Postoperative days correspond to the sessions preceding the day of picrotoxin injection into the GP or the SNr (0.165 and 0.033 nmol/μl, respectively).

  • *p< 0.05, Fisher's PLSD test, compared with preoperative performance after significant ANOVA.

  • **p< 0.05, Fisher's PLSD test, compared with postoperative performance after significant ANOVA.