Quantification of neuronal complexity
| Control | Tg/agrn−/− | |
|---|---|---|
| Number of primary dendrites per neuron | 5.6 ± 0.30 | 5.5 ± 0.31 |
| Branching points per 100 μm of dendrite | 1.10 ± 0.04 | 1.17 ± 0.04 |
| Length of dendrites (μm) | 1491 ± 73 | 1134 ± 50* |
| Spine length (μm) | 1.841 ± 0.006 | 1.731 ± 0.006 |
| Spine density (μm−1) | 0.83 ± 0.028 | 0.69 ± 0.028* |
| Spine number per dendrite | 401 ± 30.5 | 253 ± 17.6* |
Morphology of cortical pyramidal neurons in 7-week-old mice. Values derive from at least three mice of each genotype and the full reconstruction of 10 neurons from each mouse. Values are mean ± SE.
↵*p < 0.01 compared with control. For details, see also supplemental Fig. 2 (available at www.jneurosci.org as supplemental material) and Materials and Methods.