Table 1.

Named genes that are differentially expressed in E13.5 cultures after treatment with Aβ for 17 h

Probe setGenBank accession numberSymbolGene name
Named genes expressed significantly higher after Aβ treatment
    1425719_a_atBC002019.1NmiN-myc (and signal transducer and activator of transcription) interactor
    1415944_atNM_011519.1Sdc1Syndecan 1
    1426215_atAF071068.1DdcDopa decarboxylase
    1450677_atNM_007691.1Chek1Checkpoint kinase 1
    1424086_atBC025514.1OafOut at first
    1415810_atNM_010931.1Uhrf1Ubiquitin-like, containing Pumilio homology domain and RING finger domains, 1
    1424334_atBC010346.1Tspan17Tetraspanin 17
    1419669_atU97073.1Prtn3Pre-pro-proteinase 3
    1417108_atNM_029091.1Klc4Kinesin light chain 4
    1448825_atNM_133667.1Pdk2Pyruvate dehydrogenase kinase, isoenzyme 2
    1418308_atNM_008316.1Hus1Hus1
    1416763_atNM_133837.1Cdc123Cell division cycle 123
    1421915_a_atNM_009176.1St3gal3ST3 β-galactoside α-2,3-sialyltransferase 3
    1448598_atNM_011846.1Mmp17Matrix metalloproteinase 17
    1417001_a_atNM_023665.1D4Wsu53eHypothetical protein LOC27981
    1428029_a_atBC028539.1H2afvH2A histone family, member V
    1421048_a_atNM_023249.1Ypel1Yippee-like 1
    1418467_atNM_025891.1Smarcd3SWISNF-related matrix-associated actin-dependent regulator of chromatin, subfamily d, member 3
    1416492_atNM_007633.1Ccne1Cyclin E1
    1417635_atNM_011449.1Spa17Sperm autoantigenic protein 17
    1418893_atBC010287.1Pbx2Pre B-cell leukemia transcription factor 2
    1417225_atNM_022992.1Arl6ip5ADP-ribosylation-like factor 6 interactingprotein 5
Named genes expressed significantly lower after Aβ treatment
    1449451_atNM_025867.1Serpinb11Serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
    1422168_a_atNM_007540.1BdnfBrain derived neurotrophic factor
    1417065_atNM_007913.1Egr1Early growth response 1
    1451870_a_atAF461396.1Brd4Bromodomain-containing protein BRD4 shortvariant
    1421416_atNM_011944.1Map2k7Mitogen activated protein kinase kinase 7
    1417416_atNM_010595.1Kcna1Potassium voltage-gated channel, shaker-related subfamily, member 1
    1449904_atNM_026700.1Dopey2Dopey family member 2
    1416039_x_atNM_010516.1Cyr61Cysteine rich protein 61
    1415834_atNM_026268.1Dusp6Dual specificity phosphatase 6
    1451828_a_atAB033886.1mACS4 variant1Acyl-CoA synthetase 4 variant1
    1422703_atNM_008194.1GykGlycerol kinase
    1420800_a_atNM_010611.1Kcnq2Potassium voltage-gated channel, subfamily Q, member 2
    1449816_atNM_020564.1Sult-x1Sulfotransferase-related protein SULT-X1
    1422931_atNM_008037.1Fosl2Fos-like antigen 2
    1417466_atNM_133736.1Rgs5Regulator of G-protein signaling 5
    1421598_atNM_008834.1Phxr3Per-hexamer repeat gene 3
    1420696_atNM_013657.1Sema3cSema domain, immunoglobulin domain (Ig), shortbasic domain, secreted, (semaphorin) 3C
    1422256_atNM_009217.1Smstr2Somatostatin receptor 2
    1422831_atNM_010181.1Fbn2Fibrillin 2
    1421306_a_atNM_024124.1MitrMyocyte enhancer factor 2-interacting transcription repressor
    1417871_atNM_010476.1Hsd17b7Hydroxysteroid (17-β) dehydrogenase 7
    1420342_atNM_010268.1Gdap10Ganglioside-induced differentiation-associated protein 10
    1421170_a_atNM_019677.1Plcb1Phospholipase C, β
    1419681_a_atNM_015768.1Prok1Prokineticin 1
    1450336_atNM_010940.1Nsccn1Nonselective cation channel 1
    1422868_s_atNM_010266.1GdaGuanine deaminase
    1449945_atNM_133249.1Ppargc1bPeroxisome proliferative activated receptor γ, coactivator 1β
    1421738_atNM_008066.1Gabra2GABAA receptor, subunit α2
    1449999_a_atNM_009784.1Cacna2d1Calcium channel voltage-dependent, α2δ subunit 1
    1421786_atNM_024459.1Ppp3r1Protein phosphatase 3, regulatory subunit B, α isoform (calcineurin B, type I)
    1449895_atM85170.1AcrosinAcrosin
    1418025_atNM_011498.1Bhlhb2Basic helix-loop-helix domain containing, class B2
    1421199_atNM_011807.1Dlgh2Chapsyn-110
    1420912_atNM_033565.1Laf4lLymphoid nuclear protein related to AF4-like
    1419765_atNM_029402.1Cul2Cullin 2
    1418136_atNM_009365.1Tgfb1i1Transforming growth factor β 1 induced transcript 1
    1424659_atAF144628.1Slit2SLIT2
    1450288_atNM_007666.1Cdh6Cadherin 6
    1420383_a_atNM_023420.1Col4a3bpCollagen, type IV, α3 (Good pasture antigen)-binding protein
    1422823_atNM_007945.1Eps8Epidermal growth factor receptor pathway substrate 8
    1450193_atNM_010408.1Hcn1Hyperpolarization-activated, cyclic nucleotide-gated K + 1
    1419392_atNM_011995.2PcloPiccolo (presynaptic cytomatrix protein)
    1451791_atAF004833.1TFPITissue factor pathway inhibitor
    1448860_atNM_080726.1Rem2Rad and gem related GTP binding protein 2
    1421340_atNM_008580.1Map3k5Mitogen activated protein kinase kinase kinase 5
    1422785_atNM_053268.1Rasa2RAS p21 protein activator 2
    1417010_atNM_013915.1Zfp238Zinc finger protein 238
    1418589_a_atAF100171.1Mlf1Myelodysplasiamyeloid leukemia factor 1
    1417110_atNM_008548.1Man1aMannosidase 1, α
    1424800_atD10727.1ndpp-1NDPP-1 protein
    1448765_atNM_008054.1FynFyn proto-oncogene
    1418018_atNM_007754.1CpdCarboxypeptidase D
    1450656_atNM_010303.1Gna13Guanine nucleotide binding protein, α 13
    1426208_x_atAF147785.1Zac1Zinc finger protein ZAC1
    1425202_a_atU89274.1Ank3Ankyrin-3
    1450038_s_atNM_009481.1Usp9xUbiquitin specific protease 9, X chromosome
    1421970_a_atNM_013540.1Gria2Glutamate receptor, ionotropic, AMPA2 (α2)
    1424986_s_atAF391192.1Fbxw6F-box-WD40 repeat protein 6
    1450659_atNM_011880.1Rgs7Regulator of G-protein signaling 7
    1448396_atNM_018872.1Tmem131Transmembrane protein 131
    1417901_a_atNM_010492.1Ica1Islet cell autoantigen 1, 69 kDa
    1417403_atAF480860.1MasrMyelination associated SUR4-like protein
    1448736_a_atNM_013556.1HprtHypoxanthine guanine phosphoribosyl transferase
    1416636_atNM_053075.1RhebRas-homolog enriched in brain
    1450634_atNM_007508.1Atp6v1a1ATPase, H+ transporting, lysosomal 70 kDa, V1 subunit A, isoform 1
    1419047_atNM_018814.1PcnxcDNA sequence AF096286
  • Summary of named genes that are differentially expressed in Aβ-treated cultures. Microarray analysis was performed on total RNA extracted from E13.5 cultures after 17 h treatment with Aβ compared and untreated cultures.