Effect of Wnt/Fzd inhibition on olfactory connection: effect on ORN axons, at maximal concentration
| PBS | Dkk1 | sFRP2 | |
|---|---|---|---|
| Totala | 34 | 16 | 19 |
| Normal trajectory and connectionb | 28 (82%) | 2 (12%) | 0 (0%) |
| Lack of connection onlyc | 6 (18%) | 11 (68%) | 15 (79%) |
| Lack of connection and altered trajectoryd | 0 | 3 | 4 |
↵aNumber of slices in which ORN axons could be visualized.
↵bNumber of slices in which ORN axons were normally oriented and contacted the FB.
↵cNumber of slices in which ORN axons were normally oriented but failed to contact the FB.
↵dNumber of slices in which ORN axons show abnormal trajectory and (consequently) lack of connection.