Table 1.

Summary of duration of cell cycle phases for Ts65Dn and euploid forebrain precursor cells

Age	Genotype	Cortex				Hippocampus
Age	Genotype	GF	T_c − T_s (h)	T_s (h)	T_c (h)	GF	T_c − T_s (h)	T_s (h)	T_c (h)
E13.5	Euploid	1	11.8	5.7 ± 0.2	17.5 ± 0.3	1	11.3	6.0 ± 0.3	17.3 ± 0.3
	Ts65Dn	1	13.8	6.9 ± 0.3^*	20.7 ± 0.5^**	1	13.2	7.4 ± 0.3^*	20.7 ± 0.4^**
E14.5	Euploid	1	13.3	6.3 ± 0.6	19.6 ± 0.7	1	13.6	6.3 ± 0.5	19.9 ± 0.6
	Ts65Dn	1	14.9	7.4 ± 0.3^*	22.3 ± 0.4^**	1	15.1	7.9 ± 0.4^*	23.0 ± 0.5^**
E15.5	Euploid	0.92	13.9	—	—	1	14.2	—	—
	Ts65Dn	0.88	15.1	—	—	0.92	15.8	—	—
E16.5	Euploid	0.84	13.7	—	—	1	14.6	—	—
	Ts65Dn	0.8	14.4	—	—	0.9	16.1	—	—

T_s data represent mean ± SD (n = 3–4). GF, Growth fraction; T_s, duration of S-phase; T_c, duration of cell cycle; —, not determined.
↵*p < 0.01,
↵**p < 0.0003 by paired t test.