Table 1.

Voltage-gated Na+ currents in rat hippocampal neurons

CellsPeak density (pA/pF)V1/2 (act) (mV)kact (mV)V1/2 (inact) (mV)kinact (mV)
GFP−150 ± 15 (38)−27 ± 1 (22)6.0 ± 0.3 (22)−60 ± 1 (27)6.1 ± 0.2 (27)
FGF14−242 ± 24 (17)*−33 ± 1 (13)**3.6 ± 0.3 (13)***−56 ± 1 (10)**5.4 ± 0.2 (10)
FGF14F145S−61 ± 13 (29)***−22 ± 2 (9)**6.4 ± 0.3 (9)−66 ± 1 (9)**8.0 ± 0.5 (9)***
  • All values are means ± SEM; numbers in parentheses are the numbers of cells analyzed. Values are significantly different from those determined in cells expressing GFP alone at the *p < 0.01, **p < 0.005, and ***p < 0.001 levels.