Table 1.

Nerve treatment effects on LGS→MG IA EPSP amplitude and other properties recorded from MG MNs

TreatmentNumber of ratsNumber of MNs (range MN/rat)LGS→MG IA EPSP peak amplitude (mV)Rheobase current (nA)AHP half-decay time (ms)
Normal450 (9–22)1.38 ± 0.1411.84 ± 0.8111.15 ± 0.32
3 d after LGS nerve crush461 (10–21)2.86 ± 0.22*9.80 ± 0.6611.29 ± 0.14
LGS crush + daily stim proximal tibial nerve
    1 h stim on days 1–3464 (15–18)1.61 ± 0.109.25 ± 0.8611.14 ± 0.18
    1 h stim on day 2 only229 (14–15)2.36 ± 0.07*9.30 ± 1.5011.59 ± 0.45
LGS crush + daily stim distal tibial nerve443 (7–16)2.76 ± 0.12*7.48 ± 0.45*12.65 ± 0.33
LGS crush + daily stim proximal tibial nerve during lidocaine block440 (8–13)1.52 ± 0.098.23 ± 0.8112.73 ± 0.41
  • Values are mean of means from individual animals ± SEM.

  • *p < 0.01 for comparisons with normal group tested by nested ANOVA, Tukey's HSD post hoc test (see diagrams for treatment groups in Figs. 3 and 5).