Table 2.

Nerve treatment effects on IA EPSP amplitude and other properties recorded from tibial MNs

TreatmentNumber of ratsNumber of MNs (range MN/rat)Tibial→tibial IA EPSP peak amplitude (mV)Rheobase current (nA)AHP half-decay time (ms)
Normal690 (5–23)4.69 ± 0.239.86 ± 0.59 (76)17.09 ± 1.38 (76)
Tibial nerve crush575 (13–20)11.98 ± 0.79*7.15 ± 0.71* (64)17.26 ± 1.97 (62)
Tibial nerve crush + colchicine466 (10–22)5.81 ± 0.486.57 ± 0.91* (51)19.63 ± 2.37 (53)
Tibial nerve intact + colchicine5110 (14–34)5.76 ± 1.126.92 ± 0.50* (89)17.28 ± 0.57 (58)
  • Values are mean of means from individual rats ± SEM.

  • *p < 0.01 versus normal tested by nested ANOVA, Tukey's HSD post hoc test (see diagrams for treatment groups in Fig. 6).