Brain regions additionally activated in the elderly as compared to the young subjects in which performance and brain activation is positively correlated in the OLD group during NONISODIR coordination
| Region activated | Side | x | y | z | t value |
|---|---|---|---|---|---|
| Middle frontal gyrus (DLPFC) | L | −36 | 38 | 34 | 2.86 |
| Inferior frontal gyrus (pars opercularis/triangularis) | L | −48 | 20 | 24 | 4.67 |
| Anterior insula | L | −52 | 16 | −10 | 3.92 |
| Superior frontal sulcus (pre-PMd) | L | −36 | 4 | 54 | 3.71 |
| Superior temporal gyrus | L | −58 | −16 | −2 | 2.68 |
| Superior parietal gyrus | L | −18 | −62 | 56 | 3.42 |
| Cerebellar hemisphere (V) | L | −28 | −48 | −24 | 3.91 |
| Cerebellar hemisphere (VIIIB) | R | 18 | −60 | −50 | 3.40 |
The t values and localizations (MNI coordinates) of activation peaks showing a significant (p < 0.05; cluster-wise FDR correction for multiple comparisons) positive correlation between the level of brain activity and coordination performance are shown. Regions reaching significance only at an uncorrected level (p < 0.001) are in italics. L, Left hemisphere; R, right hemisphere; M, medial.