Table 2.

Correlation between [¹¹C](R)-PK11195 binding potentials and clinical variables

Brain region	[¹¹C](R)-PK11195 binding potential^a		Duration of METH use^b		Duration of METH abstinence^b		Aggression questionnaire scores^b
Brain region	Control subjects	METH abusers	τ	p	τ	p	τ	p
Midbrain	0.08 (0.03)	0.29 (0.20)^*	0.39	0.084	−0.66	0.004^*	0.44	0.046
Striatum	0.05 (0.02)	0.19 (0.13)^*	0.31	0.166	−0.61	0.008^*	0.49	0.027
Thalamus	0.04 (0.03)	0.16 (0.10)^*	0.50	0.027	−0.74	0.001^*	0.49	0.027
Orbitofrontal cortex	<0.01	0.08 (0.07)^*	0.42	0.070	−0.55	0.020	0.46	0.044
Insular cortex	<0.01	0.08 (0.06)^*	0.40	0.082	−0.53	0.024	0.44	0.052

↵^aData shown are mean (SD); the level of statistical significance was set at p = 0.01 (Mann–Whitney U test).
↵^bData shown are computed by using Kendall's τ (n = 12 for methamphetamine abusers); the level of statistical significance was set at p = 0.01.
↵*p < 0.01.