Increase in | Effects on | ||||
---|---|---|---|---|---|
Rin | |Z|max | fR | Q | ΦL | |
Vm | Increase | Increase | Bell-shaped | Bell-shaped | Bell-shaped |
Rm | Increase | Increase | Decrease | Increase | Increase |
Cm | No change | Decrease | Decrease | Decrease | Decrease |
ḡh | Decrease | Decrease | Increase | Increase | Increase |
V1/2 | Decrease | Decrease | Bell-shaped | Bell-shaped | Bell-shaped |
τh | No change | Increase | Decreasea | Nonmonotonic | Nonmonotonic |
↵aThere exists a minimal activation/deactivation time constant, τ h, required for a neuron to resonate (Hutcheon et al., 1996b; Hutcheon and Yarom, 2000), but after τ h crossed that threshold and the neuron does resonate, the resonance frequency decreases with increase in τ h. This threshold value on τ h also reduces with increase in ḡh (Fig. 3F; supplemental Fig. 3D,E, available at www.jneurosci.org as supplemental material), elucidating the complex relationships that exist between the passive and h-channel properties. For plots associated with this table, see Figure 3 and supplemental Figures 2–4 (available at www.jneurosci.org as supplemental material).