Table 1.

CRF injection induces KOR phosphorylation in specific mouse brain regions

RegionCRF-induced KORp-irRegionCRF-induced KORp-ir
Dorsal raphe nucleus+++Nucleus accumbens++
Basolateral amygdala+++Bed nucleus stria terminalis+
Dorsal hippocampus+++Caudate–putamenNot detected
Ventral pallidum++Central nucleus amygdalaNot detected
Ventral tegmental area++
  • Compiled summary of qualitative data showing brain regions positive or negative for KORp-ir after intracerebroventricular CRF injection. Positive KORp-ir is indicated in three levels of magnitude (+++, high; ++, moderate; +, lowest but above background control).