Electrophysiological properties of cold-sensitive and cold-insensitive adult rat cultured nodose neurons
| Cold sensitive (n = 7) | Cold insensitive (n = 8) | p value | |
|---|---|---|---|
| Input resistance | 340 ± 121 MΩ | 317 ± 79 M | NS |
| Resting membrane potential | −56 ± 3 mV | −56 ± 3 mV | NS |
| Firing threshold | −42 ± 1 mV | −43 ± 1 mV | NS |
| Rheobase | 52 ± 14 pA | 58 ± 13 pA | NS |
| Action potential amplitude | 98 ± 5 mV | 101 ± 4 mV | NS |
| Action potential duration | 1.00 ± 0.09 ms | 1.19 ± 0.04 ms | NS |
Neurons were recorded in the perforated-patch current-clamp configuration. Input resistance was measured from the slope of peak voltage response to a series of negative current steps. Spike duration was measured at half amplitude.