Table 1.

A comparison of characteristics of ocular dominance plasticity in the critical period and adulthood

Critical periodAdult
Time course4 d, primarily a rapid loss of responses of the deprived eye7 d, transient and slight loss of responsiveness of deprived eye, with prominent delayed potentiation of responses of both eyes
SymmetrySymmetric, similar effects of contralateral-eye and ipsilateral-eye MDAsymmetric, much larger effect for contralateral-eye MD
No effect of BDClear effect of BD, like that of contralateral-eye MD
Involvement of NMDA receptorsYesYes
Trigger for plasticityImbalance of inputsChanges in cortical activity levels
Possible role of plasticityDevelopmental rewiringCompensatory to maintain activity