Temporalis temperature (°C) | MABP (mmHg) | pH | pCO2 (mmHg) | pO2 (mmHg) | Hematocrit (%) | ||
---|---|---|---|---|---|---|---|
Ischemic preconditioning | |||||||
Saline | Pre | 34.8 ± 0.3 | 138.3 ± 4.7 | 7.43 ± 0.0 | 46.8 ± 1.8 | 101.5 ± 1.3 | 37.3 ± 1.0 |
Post | 35.0 ± 0.3 | 135.5 ± 4.1 | 7.38 ± 0.0 | 46.5 ± 0.5 | 88.0 ± 4.7 | 39.3 ± 1.2 | |
CaEDTA | Pre | 33.9 ± 0.4 | 146.0 ± 5.5 | 7.42 ± 0.0 | 44.0 ± 2.6 | 105.7 ± 3.4 | 34.7 ± 2.3 |
Post | 34.0 ± 0.4 | 146.0 ± 8.0 | 7.42 ± 0.0 | 40.7 ± 3.9 | 98.0 ± 1.5 | 35.3 ± 1.2 | |
ZnEDTA | Pre | 33.4 ± 0.6 | 148.5 ± 15.5 | 7.32 ± 0.0 | 43.0 ± 2.0 | 117.5 ± 0.4 | 42.5 ± 0.6 |
Post | 33.8 ± 0.6 | 152.5 ± 16.5 | 7.28 ± 0.0 | 50.5 ± 3.5 | 86.5 ± 8.5 | 44.0 ± 2.0 | |
ap75NTR | Pre | 36.1 ± 0.1 | 145.0 ± 15.0 | 7.35 ± 0.0 | 48.0 ± 1.0 | 85.5 ± 8.5 | 40.0 ± 4.0 |
Post | 35.9 ± 0.0 | 140.0 ± 14.0 | 7.34 ± 0.1 | 52.5 ± 5.5 | 75.0 ± 10.0 | 42.0 ± 1.0 | |
PC plus 1 tMCAO | |||||||
Saline | Pre | 35.8 ± 0.3 | 153.3 ± 6.9 | 7.44 ± 0.0 | 47.0 ± 2.0 | 96.0 ± 3.6 | 39.7 ± 0.3 |
Post | 35.7 ± 0.3 | 148.5 ± 9.0 | 7.45 ± 0.0 | 44.7 ± 1.5 | 95.7 ± 5.5 | 42.0 ± 4.5 | |
CaEDTA | Pre | 35.9 ± 0.1 | 147.3 ± 7.0 | 7.40 ± 0.0 | 47.7 ± 1.8 | 88.7 ± 2.9 | 45.0 ± 0.6 |
Post | 36.2 ± 0.2 | 136.0 ± 8.5 | 7.54 ± 0.1 | 38.3 ± 4.5 | 89.3 ± 3.9 | 44.0 ± 0.6 | |
ZnEDTA | Pre | 36.0 ± 0.5 | 135.0 ± 6.0 | 7.40 ± 0.0 | 46.0 ± 1.0 | 82.0 ± 22.0 | 35.5 ± 0.5 |
Post | 35.5 ± 0.5 | 139.0 ± 0.0 | 7.39 ± 0.0 | 44.5 ± 0.5 | 91.5 ± 2.5 | 42.0 ± 0.0 | |
ap75NTR | Pre | 36.1 ± 0.8 | 145.7 ± 6.4 | 7.43 ± 0.0 | 46.3 ± 1.8 | 95.3 ± 3.8 | 40.0 ± 1.0 |
Post | 35.8 ± 0.2 | 141.0 ± 9.5 | 7.46 ± 0.0 | 39.5 ± 3.5 | 85.5 ± 8.5 | 39.0 ± 1.0 | |
Sham plus 1 tMCAO | Pre | 36.7 ± 0.5 | 140.3 ± 10.8 | 7.44 ± 0.0 | 47.3 ± 0.0 | 103.0 ± 4.6 | 40.7 ± 0.9 |
Post | 35.9 ± 0.3 | 141.7 ± 8.4 | 7.46 ± 0.0 | 42.0 ± 2.1 | 87.3 ± 3.8 | 39.7 ± 1.7 |
Rats were treated with intraventricular injections of saline, CaEDTA, ZnEDTA, or anti-p75NTR function-blocking antibody (ap75NTR).