Table 1.

Summary of antibodies used for immunohistochemistry

Antibody	Epitopes	Type	Dilution	Resource	Reference
TTBK1	TTBK1 kinase domain	M	1:100	Ikezu laboratory	This manuscript
GFAP	Glial fibrillary acidic protein	P	1:2000	Dako	(Yamamoto et al., 2005, 2007)
IBA1	C-terminal protein	P	1:1000	Dr. S. Kohsaka	(Ito et al., 1998)
Synaptophysin	Synaptosome preparation	M	1:2000	Sigma	(Murphy et al., 2000)
Synaptotagmin	Brain synaptic junctional protein complexes	M	1:2000	Abcam	(Rastaldi et al., 2006)
Phospho-NF	Phosphorylated neurofilament	M	1:200	Dako	(Gorantla et al., 2007)
Phospho-APP	Thr668	P	1:250	Cell Signaling Technology	(Kins et al., 2003)
Phospho-GSK3α/β	Tyr279/216	M	1:200	Upstate Biotechnology	(Allen et al., 2002)
Phospho-GSK3α/β	Ser21/9	P	1:200	Cell Signaling Technology	(Allen et al., 2002)
GSK3β	C-terminal protein	P	1:200	Santa Cruz Biotechnology	(Allen et al., 2002)
PHF-1	P-tau Ser396 and Ser404	M	1:100	Dr. P. Davies	(Greenberg et al., 1992)
AT8	P-tau Ser199, Ser202, and Thr205	M	1:200	Innogenetics	(Biernat et al., 1992)
12E8	P-tau Ser262 and/or Ser356	M	1:2000	Elan Pharmaceuticals	(Seubert et al., 1995)
pS422	P-tau Ser422	P	1:100	Dr. A. Delacourte	(Bussière et al., 1999)
AT100	P-tau Ser212 and Thr214	M	1:100	Pierce	(Zheng-Fischhöfer et al., 1998)