Effect of ubMunc13-2 and ubMunc13-2W387R on the different kinetics components of the exocytotic burst
| RRP | SRP | |||
|---|---|---|---|---|
| Time constant | Amplitude | Time constant | Amplitude | |
| ubMunc13-2 | 17.85 ± 1.42 (n = 38) | 612.79 ± 86.20 (n = 38) | 440.16 ± 42.84 (n = 38) | 1063.78 ± 134.62 (n = 38) |
| Control | 19.55 ± 2.20 (n = 43) | 159.27 ± 22.42 (n = 43) | 195.08 ± 18.47 (n = 43) | 211.32 ± 22.10 (n = 43) |
| ubMunc13-2W387R | 19.18 ± 2.45 (n = 31) | 520.54 ± 67.75 (n = 31) | 286.18 ± 39.11 (n = 31) | 462.51 ± 57.54 (n = 31) |
| Control | 23.46 ± 2.89 (n = 32) | 176.83 ± 33.40 (n = 32) | 240.23 ± 28.06 (n = 32) | 214.96 ± 20.94 (n = 32) |