Table 1.

Changes in the frequency and amplitude of saltatory movements and Ca2+ transients in golli KO and overexpressing OPCs under basal conditions or after the addition of 15mm K+ to the culture medium

KO controlKOJOE controlJOE
Movement
    Frequency (cycles/h)Basal2.12 ± 0.141.41 ± 0.20*1.96 ± 0.212.01 ± 0.18
K+ activation2.42 ± 0.272.01 ± 0.31*2.50 ± 0.303.04 ± 0.22*
    Amplitude (μm/h)Basal37 ± 328 ± 2*34 ± 463 ± 5**
K+ activation51 ± 233 ± 2*48 ± 485 ± 3*
Ca2+ transients
    Frequency (cycles/h)Basal15 ± 214 ± 316 ± 116 ± 2
K+ activation17 ± 316 ± 217 ± 217 ± 2
    Amplitude (nm)Basal93.5 ± 3.158.7 ± 4.0**87.2 ± 2.2117.2 ± 3.1**
K+ activation111 ± 2.369.5 ± 5.1*108.4 ± 2.5128.4 ± 3.2**
  • Values are expressed as mean ± SEM. Asterisks in boldface values designate significant increase or decrease versus corresponding control cells:

  • *p < 0.05,

  • **p < 0.01.