Pt # | MS type | Disease duration | EDSS | Sex/age | Race | PMI (h) | # Blocks a |
---|---|---|---|---|---|---|---|
1 | SPMS | 15 years | 9.5 | M/53 | C | 17.0 | 2 |
2 | RRMS | 8 months | 6.0 | M/43 | C | 2.8 | 1 |
3 | SPMS | 23 years | 8.0 | M/46 | C | 3.0 | 5 |
4 | PPMS | 15 years | 6.5 | F/57 | C | 5.5 | 2 |
5 | SPMS | 33 years | 9.5 | M/56 | C | 3.0 | 5 |
6 | SPMS | 9 years | 8.0 | F/63 | C | 4.6 | 3 |
7 | SPMS | 35 years | 9.5 | F/61 | B/AA | 4.8 | 1 |
8 | SPMS | 25 years | 7.5 | M52 | C | 4.8 | 1 |
↵ a Every tissue block contained a periventricular demyelinated lesion. Seven blocks from four brains (1–4) also contained adjacent nonlesion areas.
SPMS, Secondary progressive multiple sclerosis; RRMS, relapsing remitting MS; PPMS, primary progressive MS; EDSS, expanded disability status scale; M, male; F, female; C, Caucasian; B/AA, black/African American; PMI, postmortem interval.