Pain processing-related areas in the absence of attentional or emotional modulations
| Region (BA) | MNI coordinates | t score | Cluster size |
|---|---|---|---|
| Contralateral ACC | 8, 14, 34 | 3.466 | 368 |
| Ipsilateral ACC | −8, 12, 34 | 3.568 | 216 |
| Contralateral insula | 32, 16, 8 | 3.737 | 13,128 |
| 42, 6, −10 | 4.773 | ||
| 42, −4, −2 | 4.246 | ||
| Contralateral S2 | 56, −14, 14 | 5.138 | |
| 62, −18, 22 | 4.111 | ||
| Ipsilateral insula | −44, 2, 2 | 3.958 | 7112 |
| −34, 2, 6 | 3.438 | ||
| −34, −2, 10 | 3.446 | ||
| −42, −8, 0 | 4.806 | ||
| −42, −10, 2 | 4.820 | ||
| −42, −14, 8 | 4.394 | ||
| −38, −16, 18 | 3.648 | ||
| Ipsilateral S2 | −50, −24, 22 | 3.541 | 1632 |
| Contralateral medialTH | 6, −24, 0 | 5.532 | 1376 |
| 2, −18, 0 | 4.839 | ||
| Contralateral S1 | 10, −42, 64 | 4.102 | 896 |
| 14, −44, 62 | 3.916 |
Thalamic and cortical regions show increased BOLD response during the alternating warm/pain condition for the painful stimuli compared with warm nonpainful baseline. Cluster size refers to the size of the cluster in cubed millimeters with t values superior to 2.5. t scores significant in global search are bolded and underlined. t scores and cluster sizes significant in the directed search are indicated in bold.