Table 2.

Critical period markers in the HVC of isolates and controls

ControlIsolate
Volume (mm3) (n)0.16 ± 0.03* (7)0.10 ± 0.05* (5)
%PV+ and PNN+ neurons0.76 ± 0.41** 0.20 ± 0.20**
%PV+ neurons0.94 ± 0.44** 0.29 ± 0.30**
%PNN+ neurons0.85 ± 0.480.71 ± 0.36
%PV with PNN79.58 ± 15.6645.91 ± 44.89
%PNN with PV90.29 ± 9.41** 28 ± 28.44**
%PNN without PV9.71 ± 9.41** 72.00 ± 28.44**
Intensity measurements
    %Nissl intensity relative to background (n)178.23 ± 49.08 (12)191.70 ± 42.39 (10)
    %PV intensity relative to background220.18 ± 41.58** 165.64 ± 35.92**
    %CS intensity relative to background291.00 ± 84.88** 203.30 ± 48.45**
  • All animals were 90 d of age. Data indicate mean ± SD. The number of animals available for percentage calculations was the same as for volume. Intensity n values are noted in the Nissl intensity columns. For given nucleus and measurement, isolate and control were significantly different (*p < 0.02, **p < 0.004, unpaired two-tailed t test).