Total occurrencesof eating chow | Total number ofchips retrieved (offered) | Chips dropped(unretrieved) | Average ± SEMchips eaten | Total of offeredeaten (% eaten) | |
---|---|---|---|---|---|
Experiment 1: infusate | |||||
Water (n = 16) | 1.0 | 46.5 (46.5) | 5.0 | 2.9 ± 0.2 | |
Sucrose (n = 15) | 1.0 | 43.0 (43.0) | 1.0 | 2.9 ± 0.2 | |
Saccharin (n = 12) | 2.0 | 33.0 (33.0) | 1.0 | 2.8 ± 0.3 | |
Salt (n = 12) | 0.0 | 35.0 (35.0) | 1.0 | 2.9 ± 0.2 | |
Quinine (n = 13) | 1.0 | 38.5 (38.5) | 3.0 | 3.0 ± 0.2 | |
196.0 (100%) | |||||
Experiment 2: nausea | |||||
Water (n = 14) | 2.0 | 71.5 (71.5) | 3.0 | 5.1 ± 0.1 | |
Salt (n = 16) | 1.0 | 81.0 (81.0) | 2.0 | 5.1 ± 0.1 | |
Quinine (n = 16) | 1.0 | 82.5 (82.5) | 13.0 | 5.2 ± 0.2 | |
235.0 (100%) | |||||
Experiment 3: LPS | |||||
LPS (n = 19) | 2.0 | 162.0 (177.0) | (15.0) | 8.5 ± 0.8 | 162.0 (91.5%) |
Saline (n = 14) | 6.0 | 141.0 (141.0) | 0.0 | 10.1 ± 0.5 | 141.0 (100%) |
303.0 (95.3%) | |||||
Experiment 4: CTA | |||||
Paired (conditioning, n = 19) | 1.0 | 49.5 (49.5) | 2.0 | 2.9 ± 0.2 | |
Unpaired (conditioning, n = 14) | 1.0 | 420.0 (42.0) | 0.0 | 3.0 ± 0.1 | |
Paired (test, n = 19) | 4.0 | 46.0 (46.0) | 0.0 | 2.7 ± 0.2 | |
Unpaired (test, n = 14) | 4.0 | 41.0 (41.0) | 0.0 | 2.9 ± 0.1 | |
178.5 (100%) | |||||
Grand total | 27.0 | 912.5 (927.5) | 31.0 (15.0) | 912.5 (98.4%) |
During testing, rats ate freely available chow infrequently but ate almost every chip offered. There were no significant differences in the number of chips eaten between groups in any of the experiments. Chips were dropped very rarely (chips dropped), but, when this occurred, rats always picked the chip back up and resumed eating. Although some LPS-injected rats were hypophagic (unretrieved), they still retrieved and ate >90% of chips offered. CTA, Conditioned taste aversion.