Table 4.

Action potential parameters from hippocampal pyramidal neurons

Threshold (mV)Amplitude (mV)Max dV/dt (mV/ms)AP min (mV)Half-width (ms)Input resistance (MΩ)
BACE1+/+−44.1 ± 1.290.3 ± 2.486.3 ± 2.3−54.6 ± 2.72.36 ± 0.34400 ± 57
BACE1−/−−45.2 ± 1.4101.4 ± 3.3*94.7 ± 2.6*−56.3 ± 2.02.63 ± 0.39450 ± 65
  • *p < 0.05, Student's t test, significantly different from BACE1+/+.