Table 1.

Induction of CSD and sustained activation of meningeal nociceptors by stimulation of the visual cortex

Cortical stimulationCSD per trialsSustained neuronal activation per CSD
Electrical13/30 (43%) a 6/13 (46%)
Pin prick22/24 (92%)13/22 (59%)
Crystalline KCl29/29 (100%)12/29 (41%)
All trials64/83 (77%)31/64 (52%)
  • a By design, the parameters of electrical pulses were suboptimal in many trials for inducing CSD in order to control for nonspecific neuronal activation.