Deficit in GSH levels in brain (anterior cortex) of GCLM −/− relative to +/+ mice at different ages
| 5–6 days old | 16–20 days old | 35–40 days old | 3 months old | |
|---|---|---|---|---|
| Percent GSH in GCLM −/− relative to +/+ mice | 17 ± 2 | 31 ± 1 | 31 ± 3 | 28 ± 2 |
Brain total GSH deficit in GCLM −/− mice. The GSH deficit is expressed as percent of GSH levels in GCLM −/− mice relative to those in +/+ mice. GSH measurements have been performed in at least four mice per genotype and per age. Data are presented by mean ± SEM.