Table 1.

Intrinsic electrophysiological properties of striatal NPY interneurons

ParameterInput resistance (MΩ)RMP (mV)AP threshold (mV)AP width 50% (ms)AP amplitude (mV)AHP amplitude (mV)AHP duration (ms)Spontaneous firing rate (Hz)LTSIh ratio
NPY–PLTS (44)744 ± 51 (310–1702)−63 ± 1 (−79 to −51)−45 ± 1 (−53 to −38)1.3 ± 0.05 (0.75–2)74 ± 1.8 (56–108)17 ± 1 (9–25)134 ± 116.4 + 0.5 (2–12) 30/4435/441.1 ± 0.005 (1.01–1.4) 43/44
NPY–NGF (19)142 ± 13* (74–260)−88 ± 1* (−95 to −79)−44 ± 1 (−48 to −39)1.25 ± 0.08 (0.74–1.9)80 ± 2 (64–101)26 ± 1* (20–32)140 ± 50/190/191 ± 0
  • All values are means ± SEM. The numbers in parentheses refer to the range of values. n refers to number of neurons from which the measurements were obtained. AP, Action potential; RMP, resting membrane potential; AHP, afterhyperpolarizing; LTS, low threshold spike.

  • *p < 0.001; #p < 0.05, Student's two-tailed t test.