Table 3.

Electrophysiological properties (perforated patch firing rate) of CRH-GFP neurons in wild-type and Gabrd−/− mice under stress and THDOC conditions

Perforated patch firing rate (Hz)Perforated patch firing rate (Hz)
nACSF10 nm THDOCnACSF10 nm THDOC
Control7.4 ± 0.86.1 ± 0.8*Gabrd−/− control10.3 ± 2.410.3 ± 2.5
Stress9.2 ± 1.711.7 ± 2.1*Gabrd−/− stress11.4 ± 1.911.7 ± 2.1
nACSF>200 μm SR95531
Control8.1 ± 2.010.8 ± 2.8*
Stress11.8 ± 2.28.7 ± 1.5*
  • * denotes significance compared to nACSF.