Baseline mIPSC kinetics and Itonic in DGCs from rats after vehicle, EtOH, EtOH + DHM, or DHM exposure/withdrawal
| Frequency (Hz) | mIPSC area (fC) | mIPSC amplitude (pA) | Rise time (ms) | Decay time (ms) | Itonic (pA) | |
|---|---|---|---|---|---|---|
| V/W | 12.2 ± 1.7 | 674.9 ± 60.7 | 32.6 ± 2.3 | 2.0 ± 0.2 | 6.9 ± 0.6 | 28.8 ± 3.1 |
| E/W | 11.4 ± 0.8 | 698.0 ± 33.7 | 38.3 ± 3.3 | 0.8 ± 0.3 | 4.0 ± 0.4 | 13.0 ± 1.0 |
| E+D/W | 12.4 ± 0.5 | 666.8 ± 34.1 | 26.2 ± 2.1 | 1.8 ± 0.3 | 7.1 ± 0.6 | 30.0 ± 2.8 |
| D/W | 13.2 ± 1.3 | 621.5 ± 68.5 | 28.5 ± 3.0 | 2.2 ± 0.3 | 7.9 ± 1.2 | 24.3 ± 2.9 |
Data (mean ± SEM) were obtained from hippocampus slice from rats 48 h after vehicle, EtOH, E+D, and DHM administration (gavage). n = 7–8 neurons from 3 rats.