Table 2.

Effect descriptions for exploratory ROIs (by anatomical group) in Study 1, including the critical differences used to determine statistical significance

Critical differenceEffect description
ψ5%ψ1%C
Frontal lobeb1.39a1.74a4Significant perfusion decrease of 1.66a in the right frontal hemisphere of the cortisol group
Occipital lobeb,d0.98a1.22a4Significant perfusion increase in the right (2.97a) and left (1.34a) hemispheres of the cortisol group
Occipital lobeb,e3.60a4.21a14Middle occipital lobe (lateral surface): Significant effect in the left (4.61a), but not the right (2.70a), hemisphere
Ιnferior occipital gyrus (lateral surface): Significant effect in the right (3.79a), but not the left (3.33a), hemisphere
Cuneus (medial and inferior surface): Significant effect in the right (5.85a), but not the left (1.09a), hemisphere
Parietal lobec1.57a1.91a60–7 min: Significant perfusion increase of 1.84a in the cortisol relative to the placebo group in the right but not the left hemisphere
10–17 min: No significant change in cortisol and placebo groups
20–27 min: Significant perfusion increase in the left (4.64a) and right (2.37a) hemispheres of the cortisol relative to the placebo group
  • aValues are in milliliters per 100 g per minute (ml/100 g/min).

  • bLack of significant higher-order interactions concerning measurement block (Table 1) signifies that the perfusion differences in the frontal and occipital lobes stretch across all postintervention CASL measurement blocks.

  • cThis interaction can be attributed to the different effect of intervention on the hemispheres and between the CASL measurement blocks.

  • dIntervention × hemisphere.

  • eIntervention × region × hemisphere.